Publications

2019

“Computational modeling of therapy on pancreatic cancer in its early stages”
Chen J., D. Weihs, F.J. Vermolen, Accepted Biomechanics and Modeling in Mechanobiology

Non-damaging stretching combined with sodium pyruvate supplement accelerate migration of fibroblasts and myoblasts during gap closure”.
Marom A., Y. Berkovitch, S. Toume, M. B. Alvarez-Elizondo, D. Weihs, , Clinical Biomechanics 62, 96-103 (2019).

Traction force microscopy in differentiating cells”.
Abuhattum S., A. Gefen, D. Weihs. In “New developments in Tissue Engineering and Regeneration”, Editors: Fernandes, P.R, da Silva Bártolo, P.J., (Springer International Publishing) Computational Methods in Applied Sciences Series, pp. (2019). ISBN 978-3-030-15370-0

 

2018

Mechanobiology of Metastatic Cancer”.
M. B. Alvarez-Elizondo, R. Rozen, D. Weihs.  In “Mechanobiology in Health and Disease”, Editor: Stefaan Verbruggen, Academic Press (Elsevier) Biomedical Engineering series, pp. 449-494 (2018).

A phenomenological model for cell and nucleus deformation during cancer metastasis”.
J. Chen, D. Weihs, M. Van Dijk, F. J. Vermolen, Biomechanics and Modeling in Mechanobiology 17(5), 1429-1450 (2018).

A model for cell migration in non-isotropic fibrin networks with an application to pancreatic tumor islets”.
J. Chen, D. Weihs, F. Vermolen. In Press Biomechanics and Modeling in Mechanobiology 17(2), 367-386 (2018).

“’Contemporary Oncology Research: A Special Issue on the Mechanobiology and Biophysics of Cancer Development and Progression
D. Weihs. Convergent Science Physical Oncology 4, 010201 (2018).

Effect of natural honey treatment and external stretching on kinematics of cell migration during gap closure”.
Y. Berkovitch, S. Toume, A. Gefen, D. Weihs, . In “Computer Methods in Biomechanics and Biomedical Engineering: Proceedings of the 14th International Symposium CMBBE, Tel Aviv, Israel, 2016”, Editors: Amit Gefen and Daphne Weihs. pp. 75-80 (2018). ISBN 978-3-319-59764-5, DOI 10.1007/978-3-319-59764-5

Proximity of metastatic cells strengthens the mechanical interaction with their environment”.
Y. Merkher, D. Weihs. In “Computer Methods in Biomechanics and Biomedical Engineering: Proceedings of the 14th International Symposium CMBBE, Tel Aviv, Israel, 2016”, Editors: Amit Gefen and Daphne Weihs. pp. 253-258 (2018). ISBN 978-3-319-59764-5, DOI 10.1007/978-3-319-59764-5

 

2017

Control of cell proliferation by a porous chitosan scaffold with multiple releasing capabilities”.
Sh. Cai, Ch. Li, D. Weihs, G. Wang. Science and Technology of Advanced Materials 18(1), 987-996 (2017).

“Taxol reduces synergistic, mechanical invasiveness of adjacent metastatic cells”.
Y. Merkher, M. B. Alvarez-Elizondo, D. Weihs. Convergent Science Physical Oncology 3(4) 044002 (2017).

“A model for cell migration in non-isotropic fibrin networks with an application to pancreatic tumor islets”,
J. Chen, D. Weihs, F.Vermolen, In Press Biomechanics and Modeling in Mechanobiology (2017).

Complex, Dynamic Behavior of Extremely Asymmetric Di-n-Alkylphosphate-Anion Aggregates, the Long-Chain Effect and the Role of a Limiting Size: Cryo-TEM, SANS, and X-Ray Diffraction Studies“.
D. Weihs et al., Journal of Physical Chemistry B 121(16), 4099-4114 (2017).

Proximity of metastatic cells enhances their mechanobiological invasiveness“.
Y. Merkher, D. Weihs, Annals of Biomedical Engineering 45(6), 1399-1406 (2017) .

Cell-gel mechanical interactions as an approach to rapidly and quantitatively reveal invasive subpopulations of metastatic cancer cells“.
M. B. Alvarez-Elizondo and D. Weihs. Tissue Engineering Part C: Methods 23(3), 180-187 (2017). TEC full final author version

Metastatic breast cancer cells adhere strongly on varying stiffness substrates, initially without adjusting their morphology“.
S. Massalha, D. Weihs. Biomechanics and Modeling in Mechanobiology 16, 961-970 (2017). For a full-text view-only version: click here.

Low-level stretching accelerates cell migration into a gap”.
S. Toume, A. Gefen, D. Weihs.  International Wound Journal 14(4), 698-703 (2017).

 

2016

Review on experiment-based two- and three-dimensional models for wound healing“.
D. Weihs, A. Gefen, F. J. Vermolen.  Interface Focus 6(5), 20160038 (2016).

Cytoskeleton and plasma membrane damage resulting from exposure to sustained deformations: A review of the mechanobiology of chronic wounds
A. Gefen, D. Weihs,, Medical Engineering and Physics 38(9), 828-833 (2016).

Asymmetry in traction forces produced by migrating preadipocytes is bounded to 33%“.
S. Abuhattum, D. Weihs. Medical Engineering and Physics 38(9), 834-838 (2016).

Printable low-cost, sustained and dynamic cell stretching apparatus”.
S. Toume, A. Gefen, D. Weihs, , Journal of Biomechanics 49, 1336-1339 (2016).

Modern Cell Biomechanics: A Special Issue on Motility and Dynamics of Living Cells in Health, Disease and Healing”.
A. Gefen, D. Weihs. Editorial for special issue in Journal of Biomechanics, Journal of Biomechanics 49, 1271 (2016).

A Phase-Contrast Microscopy-Based Method for Modeling the Mechanical Behavior of Mesenchymal Stem Cells”Mayssam Saeed, Orna Sharbani, Daphne Weihs, and Amit Gefen, , Computer Methods in Biomechanics and Biomedical Engineering 13, 1359-1362 (2016).

Modeling migration in cell colonies in two and three dimensional substrates with varying stiffnesses”.
M. Dudaie, D. Weihs, F. J. Vermolen, A. Gefen. In Silico Cell and Tissue Science 2(1), 2-15 (2015).

Mechanical cytoprotection: A review of cytoskeleton-protection approaches for cells“.
A. Gefen, D. Weihs. Journal of Biomechanics 49, 1321-1329 (2016).

 

2015

Ratio of total traction force to projected cell area is preserved in differentiating adipocytes”.
Sh. Abuhattum, A. Gefen, D. Weihs. Integrative Biology 7(10):1212-1217 (2015).

Embryonic stem cells growing in 3-dimensions shift from reliance on the substrate to each other for mechanical support”.
A. Teo, M. Lim, D. Weihs, , Journal of Biomechanics 48(10), 1777-1781 (2015).

Mechanical Interaction of Metastatic Cancer Cells with a Soft Gel“.
R. Kristal-Muscal, L. Dvir, M. Schvartzer, D. Weihs, Procedia IUTAM 12, 211-219 (2015). Open Access!!

Effects of particle uptake, encapsulation, and localization in cancer cells on intracellular applications”.
N. Gal, S0 Massalha, O. Samuelly-Nafta, D. Weihs, Medical Engineering and Physics 37, 478-483 (2015).

Quantitative measures to reveal coordinated cytoskeleton-nucleus reorganization during in vitro invasion of cancer cells”.
L. Dvir, R. Nissim, M. Alvarez, D. Weihs. New Journal of Physics 17, 043010 (2015).
Open Access!! includes video abstract!

Towards a mathematical formalism for semi-stochastic cell-level computational modeling of tumor initiation”.
F. J. Vermolen, R. van der Meijden, M. van Es, A. Gefen, D. Weihs, Annals of Biomedical Engineering 43(7), 1680-1694 (2015).

 

2013

Origin of active transport in breast-cancer cells”.
D. Goldstein, T. Elhanan, M. Aronovitch, D. Weihs, Soft Matter 9(29), 7167-7173 (2013).

Metastatic cancer cells tenaciously indent impenetrable, soft substrates”.
R. Kristal-Muscal, L. Dvir, D. Weihs, , New Journal of Physics 15, 035022 (2013).
Open Access!!

Particle Tracking in Living Cells: A Review of the Mean Square Displacement Method and Beyond”.
N. Gal, D. Goldstein, D. Weihs, Rheologica Acta 52(5), 425-443 (2013).

Cell-based coordinate system for intracellular location-dependent particle tracking analysis”.
Sh. Abuhattum, D. Weihs. Computer Methods in Biomechanics and Biomedical Engineering 16(10), 1042-1049 (2013).

Flexible blade rheometer for in-line measurement of viscosity”.
D. Weihs, T. Hadad, R.Gurka, A. Liberzon, Chemical Engineering Science 91, 130-133 (2013).

 

2012

Intracellular mechanics and activity of breast cancer cells correlate with metastatic potential”.
N. Gal, D. Weihs. Cell Biochemistry and Biophysics 63(3), 199-209 (2012).
Featured in: Mammary Cell News, Vol. 4.18 (May 10, 2012).

Novel Algorithm and MATLAB-Based Program for Automated Power Law Analysis of Single Particle, Time-Dependent Mean-Square Displacement”.
M. Umansky, D. Weihs, Computer Physics Communications 183, 1783-1792 (2012).

Aggregate Structures of Asymmetric Di-Alkyl Phosphate Anions and the Role of Conformations about the Polar Region: SANS, Cryo-TEM, Raman Scattering, 13C NMR and Selective NOE Studies”.
Sasuga, Sonoko, Weihs, Daphne, Talmon, Yeshayahu, Okabayashi, Hirofumi, O’Connor, C., Journal of Physical Chemistry B 116, 3538-3550 (2012).

Low intensity ultrasound perturbs cytoskeleton dynamics
N. Mizrahi, E. Zhou, G. Lenormand, R. Krishnan, D0 Weihs, J. P. Butler, D. Weitz, J. J. Fredberg, E. Kimmel, Soft Matter 8(8), 2438-2443 (2012).

Image-Based Algorithm for Analysis of Transient Single-Particle Trajectories
D. Weihs, D. Gilad, M. Seon, I. Cohen, Microfluidics and Nanofluidics 12(1-4), 337-344 (2012).

 

2011

Time-Dependent Micromechanical Responses of Breast Cancer Cells and Adjacent Fibroblasts to Electrical Treatment”.
M. Lia Yizraeli, D. Weihs. Cell Biochemistry and Biophysics 61, 605-618 (2011).

2010

Experimental Evidence of Strong Anomalous Diffusion in Living Cells”.
N. Gal, D. Weihs, Physical Review E 81, 020903(R) (2010).
Featured in: the Virtual Journal of Biological Physics Research 19(4) (2010).

Rheology and Microrheology of Honey as a Model Newtonian Fluid
I. Cohen, D. Weihs. Journal of Food Engineering 100, 366-371 (2010).

2007

Simulations of Complex Particle Transport in Heterogeneous Active Liquids”.
D. Weihs, M. A. Teitell, Th. G. Mason, Microfluidics and Nanofluidics 3, 227-237 (2007).

A Comparative Study of Microstructure Development in Paired Hepatic and Gallbladder Biles”.
D. Weihs, J. Schmidt, D. Danino, I. Goldiner, D. Leikin-Gobbi, A. Eitan, M. Rubin, Y. Talmon, F. M. Konikoff. Biochimica Biophysica Acta 1771, 1289–1298 (2007).

Effects of cytoskeletal disruption on transport, structure, and rheology within mammalian cells
D. Weihs, Th0 G. Mason, M. A. Teitell. Physics of Fluids 19, 103102 (2007).
Featured in: the Virtual Journal of Nanoscale Science & Technology (October 22, 2007)

2006

Bio-microrheology: A Frontier in Microrheology”.
D. Weihs, Th. G. Mason, M. A. Teitell. Biophysical Journal 91, 4296-4305 (2006).

2005

Self-Aggregation in Dimeric Arginine-Based Cationic Surfactants Solutions
D. Weihs, D. Danino, A.Pinazo-Gassol, L. Perez, E. I. Frances,  Y. Talmon, Colloids and Surfaces A 255, 73-78 (2005).

Biliary Cholesterol Crystallization Characterized by Single Crystal Cryogenic-Electron Diffraction

D.Weihs, J.Schmidt, I. Goldiner, Dganit Danino, Moshe Rubin, Yeshayahu Talmon, and Fred M. Konikoff.  Journal of Lipid Research 46, 942-948 (2005).

2003

Microstructures in the Aqueous Solutions of a Hybrid Anionic Fluorocarbon/Hydrocarbon Surfactant”.
D. Danino, D. Weihs, R. Zana, G. Oradd, G. Lindblom, M. Abe, Y. Talmon, Journal of Colloid and Interface Science 259, 382-390 (2003).

2000

Microstructural Evolution of Lipid Aggregates in Nucleating Model and Human Biles Visualized by Cryogenic Transmission Electron Microscopy”.
F. M. Konikoff, D. Danino, D. Weihs, M. Rubin, Y. Talmon. Hepatology 31, 261-268 (2000).
Featured in: The New York Times, The Jerusalem Post, and Haaretz.

 

Back to top